Purdue is a No. 2 seed averaging 81.7 points per game against a Queens squad that went just 5-9 against winning records — the talent gap here is enormous and undeniable. Both teams are fully healthy, meaning nothing stands between the Boilermakers and a dominant first-round performance. A No. 2 vs. No. 15 matchup is exactly where superior talent asserts itself, and Purdue covers at -25.5.

Queens University Royals are making their FIRST-EVER NCAA Tournament appearance after winning the Atlantic Sun Tournament title — they beat Central Arkansas in OT to get here, and nobody does it in overtime without ice in their veins! They run a sophisticated analytics-driven offense ranking 13th nationally in rim-and-3 rate, meaning they know how to generate quality shots against elite defenses. Everyone's sleeping on these Royals as a 15-seed, but 25.5 points is a mountain that first-round Cinderellas climb every single March — the Royals cover.