The Chargers head into Arrowhead without Derwin James for a third consecutive game, gutting their secondary against Mahomes and company. Kansas City's defense is healthy and Mahomes is a full practice participant, giving the Chiefs a massive talent and health edge at home. Laying -7.5 with the best quarterback in football in a rivalry game where the opponent is shorthanded is exactly the kind of chalk I back without hesitation.

Everyone's sleeping on the Chargers in a division rivalry game, but the Chiefs are banged up — Rashee Rice is DNP/questionable with a hamstring/knee issue and Khalil Mack is sitting out, meaning KC's offense and pass rush are compromised. NBC Sports analysts even noted this matchup will be closer than the line suggests, and division games at Arrowhead have a way of tightening up in the fourth quarter. Give me the Chargers and that +7.5 cushion all day long!